A Surface Plasmon Resonance (SPR) Simulation Based on Kretschmann Configuration for Glucose Detection
Abstract
Numerous studies have been conducted on the detection of glucose as the prevalence of diabetes grows in both industrialized and developing countries. a poor way of living those results in a persistent buildup of blood sugar levels over the acceptable limit. Therefore, to detect glucose concentrations, high sensitivity, label-free, and high-resolution sensors are required. A biosensor is a device or device that utilizes the molecules of living things to detect chemical materials with output in the form of electrical, thermal, or optical signals. Biosensors that are now widely developed are optical biosensors. This is because optical biosensors can make real-time measurements, have high sensitivity, simpler analysis, and lower costs. One of the basic technologies in optical biosensors is the observation of the Surface Plasmon Resonance (SPR) phenomenon. SPR is an optical phenomenon where there is a resonance between light waves and free electrons (plasma) that oscillate and travel along the metal surface layer. In this study, biosensor Surface Plasmon Resonance (SPR) simulations were carried out and the effects of varying the glucose concentration on the sensor response were examined. The modeling outcomes showed that the decline in reflectance varied with glucose concentration. In the simulation analysis, the curve obtained shows that there is a shift in the angle towards the positive x-axis. This shows that with every increase in the concentration of glucose solution there is a shift in the angle and an increase in the refractive index. A range of glucose readings that might indicate diabetic symptoms were used in the study with sensitivity was 147.84 . Herefore, this sensor type may be used to detect glucose in the concentration range for diabetic patients.
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